Since its inception, high-performance liquid chromatography technology has experienced technological improvements in all aspects, such as detectors, better accuracy and precision or new column technology. Today most technologies center on faster separation through the advent of the Vanquish UHPLC System namely UHPLC (very high performance liquid chromatography) which is equipped with smaller particles and column diameters. All these developments are in order to increase productivity, but what exactly is productivity?
Productivity has many benefits, such as higher throughput, reduced cost per sample, a greater return on investment for purchasing high-value instruments, and substantially faster yield information from a sample.
The future of HPLC will be focused on productivity. Technologies such as increasing pump pressure, reducing column particle size and diameter, or simply offering better system performance and durability can all increase productivity.
The Thermo Scientific Vanquish UHPLC system is the most advanced UHPLC instrument available today. The new Vanquish platform is designed to increase performance and repeatability without compromising quality, durability or ease of use. Vanquish platform users have everything they need to properly solve the toughest analytical challenges.
For any application – whether HPLC or UHPLC, small or large molecule, simple or complex mix – the Vanquish platform is designed to handle it all. This innovative, easy to operate and maintain platform provides good separation that pushes the boundaries of chromatography. You’ll get a highly integrated solution providing unmatched retention times and precise peak area.
Benefit from the industry-leading, easy-to-use, easy-to-use, easy-to-use, easy-to-use, easy-to-use, eWorkflow, dedicated ePanel, Open Access Chromatography Data System and smart tools. Chromeleon CDS delivers advanced system communication with intelligent control. CDS also provides a direct plugin for the Vanquish system to other manufacturers’ chromatographic data systems or data systems.
The Vanquish UHPLC system offers three types of platforms.
Vanquish Horizon UHPLC System
For the most complex and difficult samples, or for applications with short cycle times and high throughput. The Vanquish Horizon UHPLC system can run columns with smaller particles and dimensions with greater confidence for LC and LC-MS workflows.
Vanquish Flex UHPLC Systems
For tests requiring more flexibility in solvents so as to accommodate all analytical applications. The Vanquish Flex UHPLC System has proven excellence from method development to routine analysis. With binnary and quartenary pump options, the Vanquish Flex UHPLC system offers outstanding performance for LC and LC-MS workflows.
Vanquish Duo UHPLC System
Increase productivity, up-time and faster return on investment. The Vanquish Duo UHPLC system extends the benefits of the Vanquish platform through two or three workflows (dual UHPLC, tandem UHPLC and reverse gradient) in one integrated UHPLC system. Adding a second flow path can increase productivity by saving time and cost per sample without sacrificing performance, durability or ease of use.
|Comparison of Vanquish UHPLC systems|
|Vanquish Horison UHPLC Systems||Vanquish Flex UHPLC Systems||Vanquish Duo UHPLC systems|
|Unrivaled performance and throughput for applications requiring high-end UHPLC||Binary or quaternary solvent blending for fast and reliable UHPLC or flexible method development||Increase productivity with two flow paths to support three workflows|
|System pressure||Up to 1500 bar||Up to 1000 bar||Up to 1500 bar|
|Retention time precision||Best||Better||Best|
|Flow range||5 mL/min||8 mL/min||8 mL/min|
|System components||Pump||Vanquish Binary Pump H||Vanquish Binary Pump F||Vanquish Dual Pump F|
|The pump with the highest backpressure at 1500 bar, and ideal for any gradient performance from shallow to ballistic||UHPLC performance for demanding routine applications up to 1000 bar||Uniquely provides two independent ternary-solvent blending flow streams in one device up to 1000 bar|
|Instrument can also be configured with a combination of Vanquish Horizon or Vanquish Flex pumps|
|Vanquish Quaternary Pump F|
|UHPLC performance with more solvent flexibility up to 1000 bar|
|Autosampler||Vanquish Split Sampler HT||Vanquish Split Sampler FT||Vanquish Dual Split Sampler FT/HT|
|Excellent precision, accuracy, and short cycle times with innovative air-stream cooling and barcode reading for inventory management for all workflows up to 1500 bar||Enjoy the same benefits as the Vanquish Split Sampler HT for applications up to 1000 bar||Unique sampler that combines two injection devices in one housing resulting in two separate channels that are individually controllable (Inj. volume, wash cycles, etc.) with a 1000 bar or 1500 bar option|
|Instrument can also be configured with a single Vanquish Split Sampler HT/FT|
|Extended sample capacity||Vanquish Charger|
|An intelligent, robotic rack and plate feeder that automatically loads samples in the autosampler and extends the sample capacity of all Vanquish samplers to up to 8832 samples (23 wellplates or 12 vial racks) with innovative air-stream cooling and barcode reading for inventory management|
|Column compartment||Vanquish Column Compartment|
|Provides two column thermostatting modes (still and forced air), active and passive solvent pre-heating and post column cooling for optimized control of your separations and advanced method transfer|