Thermo ScientificTM Q ExactiveTM HF-X Hybrid Quadrupole-OrbitrapTM Mass Spectrometer rises to the occasion and sets new standards in sensitivity, performance, and productivity. The Q Exactive HF-X Mass Spectrometer uses a high-capacity transfer tube for maximum ion loading, an electrodynamic ion funnel that accommodates and transmits ions over a broader mass range, and a high-field Thermo ScientificTM OrbitrapTM mass analyzer. Together, these components enable fast identification and analysis of peptides, label-free, and TMT quantitation, top-down proteomics analyses, sophisticated DDA and DIA, dRT-PRM and BioPharma characterization.
Understanding biomolecules as drug targets, disease markers, and therapeutic agents demands highly sensitive analysis of complex biological samples, without sacrificing robustness and speed. The Thermo Scientific™ Q Exactive™ HF-X hybrid quadrupole-Orbitrap™ mass spectrometer rises to the challenge as a versatile platform, setting new standards in sensitivity, performance, and productivity for any workflow. Building on the proven performance of the Thermo Scientific™ Q Exactive™ hybrid quadrupole-Orbitrap™ MS family of instruments, the new Q Exactive HF-X mass spectrometer couples a high field Thermo Scientific™ Orbitrap™ mass analyzer with a high capacity transfer tube and electrodynamic ion funnel that maximize ion loading and transmit ions over a broad mass range.
As a result, the instrument delivers a bright, focused and iron-rich beam, which translates to high sensitivity and excellent stability in analysis quality from run to run. Smart instrument control features match the superior ion transmission with increased acquisition speed and even more sophisticated data-dependent acquisition and analysis strategies to meet data quality needs at every stage of your work, from discovery to verification and quantitation.
The Q Exactive HF-X mass spectrometer boosts productivity in protein identification while maintaining the superb accuracy of the high field Orbitrap mass analyzer. Superior ion transmission, together with new scan rates up to 40 Hz, drive more efficient use of the Orbitrap mass analyzer. As a result, the Q Exactive HF-X mass spectrometer takes half as long to perform a typical proteomic analysis as the Thermo Scientific™ Q Exactive™ HF hybrid quadrupole-Orbitrap™ mass spectrometer. This results in up to 40% more unique peptide identifications per unit time, so you can shorten your time-to-results at any throughput scale and at any depth of analysis.