Thermo Scientific™ iCAP-RQ Series – Inductively Coupled Plasma Mass Spectrometry (ICP-MS)


Trace elemental analysis techniques are used for the identification and quantification of elements in a wide variety of samples. Since ICP-MS is a technique with high sensitivity and specificity, it is typically used in applications where the lowest limits of detection are required. The Thermo Scientific™ iCAP™ RQ ICP-MS was developed around the three key principles of simplicity, productivity, and robustness in order to meet with real user requirements. Minimized maintenance and exceptional, its user-friendly design resolves the problems faced everyday smoothly by routine labs. The simple, intuitive workflows facilitate implementation of new applications to cover the most pressing and changing analytical requirements.

Choose the Thermo Scientific™ iCAP™ RQ ICP-MS for a complete multi-element analysis solution for your high-throughput routine lab! With comprehensive interference removal for assured data accuracy and intuitive workflows to boost productivity, this single quadrupole (SQ) ICP-MS will expand your analytical capabilities.\

A technique involving the introduction of liquid samples that are desolvated, vaporized, atomized, and ionized in an argon plasma. Each element has a different mass and, once ionized, forms its own characteristic mass spectrum. An ion counting detector counts the number of ions at each mass-to-charge ratio, which is directly proportional to the concentration of each element in the sample.

In order to cover a broad range of different applications, the iCAP RQ ICP-MS is equipped with proprietary skimmer cone insert technology that allows the operator to easily optimize the characteristics of the instrument. The insert portfolio comprises a standard “High Matrix” insert to cover most applications, a “High Sensitivity” insert for ultra-trace analyses, and a “Robust” insert where higher matrix tolerance is needed.

For effective interference removal in single quad ICP-MS instruments, collision/reaction cells (CRCs) are most commonly used. CRCs may be operated in different ways depending on the nature of the interference that has to be eliminated, however, the most comprehensive approach is the use of an inert gas, such as He, and the use of Kinetic Energy Discrimination (KED).

In KED, unwanted polyatomic interferences are filtered out based on the difference in collision cross-section sizes of the analyte and polyatomic interferences. In addition, the proprietary design of the Thermo Scientific QCell™ CRC adds an automatically configured low mass cut-off to the interference removal toolbox, which filters out unwanted precursor ions. These ions are then unable to recombine later in the QCell CRC, backgrounds are reduced further than KED alone and detection limits are improved.

The iCAP RQ ICP-MS system with its integrated Thermo Scientific™ Qtegra™ ISDS Software demonstrated excellent performance to provide a significant improvement to analytical laboratory capabilities through simplicity, productivity and robustness. The flexible configuration delivers a complete solution for a wide range of trace elemental analysis in both research and routine applications.

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